The team competed against Israel, the Dominican Republic, Venezuela and Nicaragua in the 2023 World Baseball Classic in March 2023 in Miami, Florida.

After debuting in the amateur predecessor to the Baseball World Cup, the team won its first medal by finishing second in 1947, a performance that it repeated the following year.

Between 1942 and 1943, Puerto Rico did not participate due to the ongoing World War II to which several LBPPR players were drafted.

Returning in 1947, Puerto Rico won the silver medal, having entered the round robin tied with a record of 6–2, defeating Nicaragua to advance before losing to the host, Colombia, in the finals.

The team was headlined by Sotero Ortiz who scored more runs (21) and stole more bases (10) than anyone else, while teammate Ramon Maldonado hit 8 doubles to lead the statistic.

In 1971, Puerto Rico finished tied with Nicaragua in the third place with a record of 6–3, but did not receive the bronze medal due to their individual series.

The team was managed by Roberto Clemente (only weeks prior to his death) and featured a no-hitter by Sandalio Quinonez against Costa Rica.

A splinter cell of the national team won the bronze at the event's Federación Mundial de Béisbol Amateur version with a record of 8–2.

Eventually the FIBA and FEMBA merged and the event had only one sanctioning body, the International Amateur Baseball Association (IABF).

In 1974, Puerto Rico finished tied for fourth place at the Amateur World Series along Canada, Italy, Chinese Taipei and the Dominican Republic.

In the 1976 World Amateur Series, Puerto Rico won Silver with an 8–2 round-robin before leaving the tournament prior to the final round.

After missing the 1978 edition of the World Amateur Series, the team came back in 1980, but finished tied in the 7th place with Venezuela with a 4–7 record.

After missing out another version of the Amateur World Series, the team returned in 1984, finishing behind Panama with a record of 6–7, despite gathering a 54–46 advantage in runs.

Beginning during the last years of the 1980s and extending throughout the 1990s, Puerto Rico saw a major increase in its production of high-caliber players, with a crop that included Iván Rodríguez, Roberto Alomar, Bernie Williams, Rubén Sierra, Jorge Posada, Juan González, Carlos Delgado, Edgar Martínez and Carlos Beltrán among several others.

Top performers were 1B Efrain Garcia (.448/.484/.724, 8 RBI in 7 games), C Jose Lorenzana (.400/.455/.500), RF Joel Perez (.318/.348/.682) and P Nelson Sanchez (1–1, 2.25).

Randy Ruiz (.346/.452/.654), CF Jesus Feliciano (.378/.410/.649, 10 R, 9 RBI) and Edwards Guzman (.343/.375/.543) led the offense However, former MLB player Angel Echevarria had a weak performance with averages of .083/.241/.125.

Puerto Rico debuted in the inaugural World Baseball Classic by hosting Pool C on March 7, 2006, and defeating Panama with a score of 2–1.

Puerto Rico closed the first round by winning Pool C with a 12–2 mercy rule victory over the defending world champion, Cuba.

The final cut included infielders Alex Cintrón, Rubén Gotay, Melvin Falú, Carlos Rivera and Angel Sánchez; catchers Orlando Mercado, Jr., Stephen Morales and Raúl Casanova; pitchers Luis Atilano, Mario Santiago, José Santiago, Orlando Román, Juan Padilla, Angel García, Richard Rodríguez, Miguel Mejía, Alexander Woodson, Nelvin Fuentes, Melvin Pizarro and Efraín Nieves as well as outfielders Miguel Negrón, Luis Matos y Miguel Abreu.

Journalist Duldin Meléndez of Periodico La Cordillera wrote in a piece that "[Pérez] is not familiar with the [amateur] players and has not even seen them play" expressing a similar concern about the Federation's president, Israel Roldán.

Juan Carlos Díaz, infielder of the Bravos de Cidra in Béisbol AA, openly expressed disappointment when he did not receive an invitation, noting that he deserved it after leading the Liga Caribe division with an average of .632 and the league's final in offensive.

The team was mostly composed of professional players such as Víctor Raúl González, Orlando Mercado, Jorge Jiménez, Philip Cuadrado, Adrián Ortiz, Efraín Nieves, Ricard Rodríguez Nick Ortiz, Armando Ríos, Christopher Amador, Edwards Guzmán and Mario Santiago, but also included three amateurs, Antonio Acevedo, Joycet Feliciano and Manuel Romero.

Several players from the Minor Leagues who were unable to compete at the Central American and Caribbean Games, because this event was not sanctioned by the IBAF, now joined the pre-selection.

The most notable addition was González, who was joined by Fernando Cabrera, Kiko Calero, Federico Báez, Saúl Rivera, Ramón Vázquez, Gabriel Martinez, Luis Figueroa, Jorge Padilla, Alex Cora and Christian Colón.

During this time frame the team was immersed in a change of the guard, losing MLB All-Stars Iván Rodríguez, Carlos Delgado and Bernie Williams to retirement.

The date of the 2014 Central American and Caribbean Games has opened the door for Puerto Rico and several other teams to reinforce themselves with MLB players, raising the competitive level of what is usually a low caliber tournament.

For secondary competitions, former MLB player Juan González was named as manager making his debut at the 2018 Central American and Caribbean Games.

[17] Unable to request athletes contracted to MLB (or active in MiLB), he assembled a team composed by players active in foreign independent leagues, the local Doble A amateur league and veteran free agents with previous professional experience, making the final cut following a preparatory tournament.

Once again managed by González, Puerto Rico won the gold medal of the 2019 Pan American Games, going undefeated and besting Canada 6:1 in the final.

[29] The team competed against Israel, the Dominican Republic, Venezuela and Nicaragua in the 2023 World Baseball Classic in March 2023 in Miami, Florida.