In 1870, a native of Po-li-sia named Khai-san received treatment for a medical issue in a missionary hospital in Taiwan-fu (present-day Tainan) and learned about Christianity.

Tungmen, Pacheng, Pipa, Shuitou, Qilin, Zhuge, Xinan, Ximen, Nanmen, Beimen, Beian, Beimei, Taian, Danan, Wugong, Tongsheng, Qingxin, Xunhua, Dacheng, Lancheng, Taomi, Chenggong, Nancun, Ailan, Tieshan, Fangli, Xiangshan, Yixin, Gecheng, Guangcheng, Shigang, Fuxing and Niumian Village.

It is located in the mountainous center of Taiwan, and many tourist destination spots, such as Sun Moon Lake are nearby.

Puli is at one end of National Highway 6 which provides a connection with west Taiwan towards Taichung and Nantou City.

At the eastern end of the Highway the Puli exit connects to the Hehuanshan mountain pass, at its highest point 3275 meters above sea level, before the road continues to Hualien on the east coast.