In 2010 he anchored the Zee TV music talent hunt Sa Re Ga Ma Pa Singing Superstar.

[3] He has also featured in television ads for Colgate, Pizza Hut, Compaq Presario, Amaron Batteries and Castrol.

Kohli made his acting debut in films with Bas Yun Hi (2003) starring opposite Nandita Das.

[9] Purab played the role of a divorced lawyer in the 2012 movie Kuch Spice To Make It Meetha with actress Nauheed Cyrusi and composer Kavish Mishra.

Purab Kohli appeared as Angad Shergil in the Voot web series It's Not That Simple (2018), with other featured cast Swara Bhaskar, Sumeet Vyas, Vivan Bhatena, Manasi Rachh, Neha Chauhan, Karan Veer Mehra, Devika Vatsa, Rohan Shah, Jia Vaidya.

He switched his education faculty from Science to Commerce and finally to Arts and studied Economics, Psychology and Literature.

[11] Kohli married his long time girlfriend, a British yoga teacher named Lucy Paton in 2016.