They released three studio albums—Lord Willin' (2002), Hell Hath No Fury (2006) and Til the Casket Drops (2009)—to mild commercial success; the former spawned the Billboard Hot 100-top 40 singles "Grindin'" and "When the Last Time", for which they became best known.

He guest featured on West's single "Runaway" in October of that year—which peaked at number 12 on the Billboard Hot 100—as well as his song "So Appalled" also from the album.

In early 2001, Pharrell Williams signed the duo to Arista Records through his recently established Star Trak imprint.

[11] Due to contractual requirements, Clipse was forced to stay on Jive, while Star Trak and the rest of its roster moved to their new home at Interscope Records.

[11] While Clipse resumed work on the album, and eventually finished recording it, the duo became increasingly frustrated with Jive, as the label was notorious for overlooking various hip-hop/R&B artists in favor of more pop-oriented acts on its roster.

[15] The follow-up to Hell Hath No Fury, titled Til the Casket Drops, was released on December 8, 2009, via Columbia Records.

[11] After releasing their third album, Pusha T and Malice announced Clipse would be going on indefinite hiatus so the brothers could focus on their solo careers.

Shortly after this, Pusha T was signed to Kanye West's GOOD Music label in September 2010, and made his first appearance as a member of the GOOD roster on Kanye West's My Beautiful Dark Twisted Fantasy, appearing on his hit "Runaway" and premiering the song with him at the 2010 MTV Video Music Awards on September 12, 2010.

[31] After the release of his EP, Pusha T started working on his solo debut studio album, which would be executively produced by Kanye West.

On October 19, 2011, via Twitter, Kanye West announced plans for a Spring 2012 GOOD Music album, featuring all artists from the label as well as numerous guest appearances.

In October 2012, Pusha T made an appearance on the soundtrack to the film The Man with the Iron Fists on a track titled "Tick Tock" alongside fellow American rappers Raekwon, Joell Ortiz and Danny Brown.

Pusha T's debut studio album was released on October 8, 2013, featuring guest appearances from Rick Ross, Young Jeezy, 2 Chainz, Big Sean, Future, Pharrell Williams, Chris Brown and Kendrick Lamar, among others.

[47][48] The album includes production from Kanye West, The Neptunes, The-Dream, Just Blaze, No I.D., Nottz, Don Cannon and Swizz Beatz, among others.

[66] The album garnered controversy when West spent $85,000 to acquire the cover art: a photo of Whitney Houston's drug-filled bathroom, taken in her Atlanta, Georgia residence in 2006.

Not only did the content of the album cover cause outside controversy, but Pusha T claims to not have agreed with the price West paid for the photo.

[72] In February 2020, Pusha T started a new record label, Heir Wave Media Group, to sign and develop artists from the Virginia area.

In creating the label, Pusha cited his desire to recruit "album artists" who craft narratives and larger stories throughout their projects.

[73][75] On February 7, 2022, Pusha T released "Diet Coke", the lead single from his fourth studio album It's Almost Dry, which was produced by Kanye West and 88-Keys.

[81] The much-delayed album, primarily produced by frequent collaborators Pharrell Williams and Kanye West, was released on April 22 to widespread critical acclaim.

[83][84] In December 2022, Pusha T announced his departure from GOOD Music after founder Kanye West's antisemitic and pro-race remarks.

Speaking on West's support for "White Lives Matter", his 2024 presidential campaign and other public outbursts, Pusha T stated that they were nothing to "tap dance around".

[90] On July 22, 2011, Consequence released a song titled "The Plagiarist Society" where he takes shots and questions Pusha T's coke-dealing raps.

Towards the end of the record, the Queens native promises to take aim at Kanye West next saying "You're nothing but a body shield, for that coward from the mid-west/ so yes you can bet, that your boss is next".

On August 19, Consequence released Movies on Demand 3 and continued to diss his former label and Pusha T on songs such as "Career Killer" and "Mr.RapFix (Hot Water)".

"[95][96] The tension between Pusha T and rapper Lil Wayne had been going on for years, beginning soon after Clipse and Birdman worked on "What Happened to That Boy", the latter's 2002 single.

[101] In late November 2012, Pusha T once again dissed Wayne and Birdman on a Ludacris song titled "Mad Fo" from his #IDGAF mixtape.

"[108] The song debuted on Hot 97 and has lines directed towards rumors Drake has an illegitimate child[109] and his producer's multiple sclerosis.

The song's cover art also attracted controversy, showing an unedited picture of Drake wearing a Jim Crow t-shirt and hoodie and blackface makeup.

"[112] In a June 2016 interview, former record executive Steve Stoute claimed that Pusha T had allegedly written the McDonald's "I'm lovin' it" jingle.

[123] The child's name attracted reactions online for "Brixx" being an apparent slang term for cocaine, something which Pusha T raps about often.