[2] He was forced to serve as Minister for Commerce from 3 February 2021 to 19 August 2022 in the aftermath of the 2021 Myanmar coup d'état by the Burmese military.
In the 2015 general election, he ran for House of Representatives seat from Manyangone Township but lost.
2, representing the Union Solidarity and Development Party but defeated the National League for Democracy candidate by a landslide.
[8][9] On 17 May 2021, the U.S. Department of the Treasury added Pwint San to its Specially Designated Nationals (SDN) list.
[10] On 20 July 2023, the EU countries imposed personal sanctions on San, citing his continued contributions to serious human rights violations in Myanmar as Union Minister of Labour and previously Minister of Commerce in the junta-appointed government.