A pyrena or pyrene (commonly called a "pit" or "stone") is the fruitstone within a drupe or drupelet produced by the ossification of the endocarp or lining of the fruit.
[1] It consists of a hard endocarp tissue surrounding one or more seeds (also called the "kernel").
[2][3] The hardened endocarp which constitutes the pyrene provides a protective physical barrier around the seed, shielding it from pathogens and herbivory.
[5] The hardening of the endocarp of a developing drupe occurs via secondary cell wall formation and lignification.
The biomineralisation of pyrenes during the life of the plant can aid the preservation of fruit remains in archaeological findings.