[2] In a small (n=88) malaria study in Camaroon, pyronaridine had a 100% cure rate, compared with 60% for chloroquine.

[3] It is one of the components of the artemisinin combination therapy pyronaridine/artesunate (Pyramax).

[4] It has also been studied as a potential anticancer drug,[5] and treatment for Ebola.

The combination of pyronaridine and artesunate has been evaluated to have a synergistic effect of stronger antiviral effect and less toxicity.

[6] The combination of pyronaridine and artesunate is being studied as a possible treatment for moderate to severe SARS-COV-2.