Pyrrolidine alkaloids

[1] Alkaloids with partial pyrrolidine structure are usually sub-categorized based on their occurrence and biogenetic origin.

Hygrin and cuscohygrin were isolated from the leaves of the coca shrub,[2] while (-)-codonopsinine was isolated from the woodland vine tiger bell.

[3] Among the most important representatives of the pyrrolidine alkaloids are hygrin and cuscohygrin.

[3] Furthermore, ruspolinone, norruspolinone and norruspoline also belong to this alkaloid group.

[4] Many plants containing cuscohygrin are used in the folk medicine of various peoples as sedatives or narcotics.