Pyxine pustulata is a species of corticolous (bark-dwelling), foliose lichen in the family Caliciaceae.

[1] Found in Botucatu, Brazil, it was formally described as a new species in 2014 by lichenologists André Aptroot and Patrícia Jungbluth.

The type specimen was collected by the authors from the botanical garden on the campus of Botucatu (São Paulo) at an altitude of 850 m (2,790 ft).

The lobes comprising the thallus are 0.7–1.2 mm wide, with rounded tips, and are sparsely covered with white spots (maculae).

The cortex of the thallus contains lichexanthone, a lichen product that causes it to fluoresce yellow when lit with a long-wavelength UV light.