Route 354 (highest elevation: 507 ft) is an east-west regional road in Quebec, Canada, starting from Route 159 north of Ste-Anne de la Pérade going to St-Raymond.

Between St-Casimir and Ste-Anne-de-la-Pérade, it is named the "Rapide Nord", where it is the only part it is on the north shore of the river.

Once it crosses the Rivière Ste-Anne, in the village of St-Casimir, it takes the name of rue (street) Notre-Dame.

After Chute-Panet, arriving to St-Raymond, the route uses the name of rue (street) St-Pierre.

Right after passing Ste-Christine, there is the "Pont des Cascades", where canoers can start their expedition on the rivière Ste-Anne.