[3] It provides general medical and surgical services to the residents of Western and Southern districts and is a tertiary referral centre for the whole territory of Hong Kong and beyond.

Queen Mary Hospital had its foundation stone laid on 10 May 1935 by the governor of Hong Kong, William Peel, and was officially opened on 13 April 1937 by Andrew Caldecott, the then governor of Hong Kong.

[4][5] The hospital was named for Mary of Teck, the widowed queen consort of King George V of the United Kingdom.

The Main Block (Wing A to E) is listed as a Grade III historic building.

The Nurses Quarters is listed as a Grade II historic building.