Later, experiencing the breakdown of her marriage, Twain divorced her longtime husband and songwriting partner, music producer Robert John "Mutt" Lange, in 2008.

Twain underwent vocal therapy after being diagnosed with dysphonia and Lyme disease, which caused her to nearly lose her singing voice;[7] after which she embarked on a concert tour and Las Vegas residency before releasing Now in 2017.

[8] On October 28, 2022, she announced that she will embark on her Queen of Me Tour to promote the album, which is scheduled to begin in Spokane on April 28, 2023, and will end on November 14, in Vancouver, encompassing 76 dates.

"[21] According to Ed Power of the Irish Examiner, "the 'Shania-issance' is in full swing", describing the album as "unashamedly pop" yet "Twain’s country roots are not entirely obscured".

[20] Allison Hussey of Pitchfork described the album as "a dozen tracks of optimistic affirmations and pumping electro-pop rhythms", but found the material "ill-suited to Twain's voice" and the lyrics rife with "forcibly modern idioms", concluding that Queen of Me "tries so hard to capture current trends that it already sounds behind the times".

[23] Billy Dukes of Taste of Country summarized that the album "feasts on contagious hooks and repetition",[27] while Jon Freeman of Rolling Stone defined it as "an uplifting statement about being your own champion in the present".

[28] Annabel Ross of The Sydney Morning Herald wrote that Twain is "back to her poppy, peppy self... maintaining an upbeat vibe throughout.

In a more critical review of the album for AllMusic, Stephen Thomas Erlewine claimed that, "There's no question that she's game -- she throws herself into the songs, not hesitating when "Pretty Liar" calls for her to curse—and her spirits are so high they nearly counter the cacophonic cheer of the production.