A character inspired by Quire and credited as "Kid Omega" appears in the 2006 film X-Men: The Last Stand, portrayed by Ken Leung.

Grant Morrison has cited The Sekhmet Hypothesis as an influence on the story as well as Quire's angry punk rock aesthetic, referring to it in their book, Supergods.

[3] Quentin Quire joins the student body of the Xavier Institute after Professor X's return from averting a war with Genosha and the rebuilding of the X-Mansion.

He goes to town, getting a haircut reminiscent of Bolivar Trask's depiction of a mutant overlord from The Daily Bugle that was published the day Quire was born.

Quire becomes strongly opposed to a policy of tolerance with humans, calling for vengeance for the recently murdered mutant designer Jumbo Carnation.

However, the altercation is not officially ended until the Stepford Cuckoos, led by Sophie, use Cerebra and a dose of mutant drug Kick to boost their shared powers.

A young boy, wearing a Phoenix costume and Quentin's distinct pink haircut, is seen telling Jean Grey, who vaguely recognizes him, that she doesn't have long to set the events in the timeline right.

Just prior to his arrival on the scene, the X-Men get the Phoenix to inhabit Emma Frost, Cyclops's current lover, and imprisons both her and Scott inside a containment vessel.

Finding life on a higher plane to be "boring," Quentin revives himself and decides to become a villain and secretly destroy Utopia, claiming that the X-Men stole his idea to create a mutant nation.

He elects to make his endeavor a game and selects Martha (a disembodied mutant brain with telepathic abilities living in a life support container) to be his nemesis, giving her seven and a half minutes to stop him.

Martha realizes that Quentin has infiltrated Cerebra in order to destroy the island and take revenge on the Stepford Cuckoos by putting them in a mental loop.

Thinking his containment unit just malfunctioned, Quire decides to celebrate his new freedom by infiltrating an international arms conference in Switzerland (where Scott Summers was to be giving a talk) and forcing the top leaders of the world to reveal their deepest, darkest secrets on camera.

He is released into Wolverine's custody and Quire is to attend the newly reformed Jean Grey Institute for Higher Learning in an effort to rehabilitate him.

Quire finds the effort extremely taxing to the point where he loses control of his own creation, leaving Wolverine's body a beastly, raging nightmare hellbent on killing Quentin.

Over time, Quire begins to accept his fellow students by first helping them save the faculty after Frankenstein's Circus hypnotizes them against the student body, working as a team during a field trip to the Savage Land in which Wolverine's half-brother Dog Logan makes an unexpected appearance, and in A+X, he assists Captain America in a mission against an army of MODOK clones as part of his punishment for what he did at the UN conference in Switzerland.

[20] After several members of the Jean Grey School defected to join the new Hellfire Academy, Quentin followed them, hoping to discover why Idie Okonkwo switched sides.

Due to his anger towards Logan and others, Quire later breaks off association with the facility when he becomes independently wealthy and leaves the school to join the Phoenix Corporation, later becoming the new White King of the Hellfire Club.

[21] The events of AXIS and Wolverine's death cause him to finally return to the Jean Grey School and help both the Avengers and X-Men battle Red Onslaught.

When Kitty Pryde relocated the X-Men in New York and the school was renamed to Xavier Institute for Mutant Education and Outreach, Quentin was forced to join in.

[24] Having become fed up with people, Quentin decided to exile himself from society and live in the middle of the Atlantic Ocean with Krakoa taking the shape of a small desert island.

Quentin's little vacation was interrupted by Thor, who had been directed by Kid Gladiator and Warbird for help after a conflict with the Shi'ar escalated to a cosmic scale.

[27] Kid Omega joined West Coast Avengers, under leaderships of both Hawkeyes, Clint Barton and Kate Bishop, to get financiers by starring in a reality show following their exploits.

[19] In the miniseries X-Men: Phoenix – Endsong, Quire generates massive amounts of telekinetic energy which manifest in the form of tentacles, allowing him to break free of his containment chamber, blast through the Xavier School's foundation, pull Sophie's body out of the ground, restructure it a bit, instantly heal wounds on his body inflicted through Wolverine's claws, and fly at supersonic speed.

Quire has become depressed because of an unrequited crush on Sophie of the Stepford Cuckoos; his unpopular status among the Institute students; and especially the revelation that he was an adopted child, which shatters his already fragile self-esteem.

[5] At Quire's request, all members tattoo themselves with a symbol formed by an Omega with an X below it and dress up with red-and-black striped shirts, jeans and whips.

This is an outfit designed by Carnation himself and based on an illustration from an anti-mutant article written by Bolivar Trask many years ago, which portrayed mutants enslaving the human race.

[7] In this harsh reality, it is revealed that Quentin was examined by the Shadow King and found to be an unstable, mildly talented telepath with apparently no usefulness to Weapon Omega.

As it turns out, Prophet had secretly cloned Quentin's powerful mutant brain in order to be used to trap the Shadow King.

Unable to navigate Quentin's labyrinth of a mind, the Shadow King was successfully taken off the board before the final battle against Weapon Omega.

Backed up only by bamfs, Wolverine is confronted with Quire's newest surprise: two million Negative Zone mutants in need of schooling.