The Biblioteca Queriniana is a public library with a rich collection of ancient manuscripts, located on Via Giuseppe Mazzini in Brescia, region of Lombardy, Italy.

The library was founded in 1747 and owes the nucleus of its collection to Cardinal Angelo Maria Querini (1680–1755).

The library was founded by the cardinal, who commissioned the architect Antonio Marchetti to design a building to house the institution.

Over the centuries, the collection has increased, with the addition of libraries from suppressed Catholic monasteries and churches and the donations of private individuals.

Eighteenth-century Italy had a number of examples of public libraries endowed by Catholic church leaders, including the Biblioteca Forteguerriana and Fabroniana of Pistoia and the Biblioteca Marucelliana of Florence.