[12] Priester split the 2022 season between the Single–A Bradenton Marauders, Greensboro, Double–A Altoona Curve, and Triple–A Indianapolis Indians.

[15] He made his MLB debut that day as the starting pitcher against the Cleveland Guardians; in 5+1⁄3 innings, he allowed 7 runs on 7 hits and 2 walks with 2 strikeouts, earning the loss.

[16] In 10 games (8 starts) during his rookie campaign, Priester struggled to a 7.74 ERA with 36 strikeouts across 50 innings pitched.

Priester was optioned to Triple–A Indianapolis to begin the 2024 season after he was beat out by Jared Jones for the final rotation spot.

[18] On July 29, 2024, the Pirates traded Priester to the Boston Red Sox in exchange for Nick Yorke.