Régis was born in Xanxerê, Santa Catarina, and represented Chapecoense as a youth.
Ahead of the 2019 season, after being regularly used with the under-23 squad in the previous campaign, he was promoted to the first team.
Régis made his first team debut on 20 January 2019, coming on as a late substitute for Yann in a 0–0 Campeonato Catarinense away draw against Metropolitano.
[1] Rarely used by manager Claudinei Oliveira, he became a regular under new manager Ney Franco, making his first start on 21 April and scoring the opener in a 1–1 draw at Avaí, as his side lost the state league on penalties.
[3] On 19 August 2023, Armenian Premier League club Pyunik announced the signing of Régis.