[2] The R1 plasmid imparts multi-drug antibiotic resistance to its host bacteria.
[4][page needed] R1 must rely on a "Type II" segregation system.
The par system determines the position of the replicon, ensuring that at the end of DNA Replication, the plasmid copies are well-positioned to start cell division.
ParM produces two important cytoskeletal proteins, MreB, and actin.
ParM is directed to move the plasmid copies to opposite cell poles.