The R25 is a provincial route in South Africa that connects Johannesburg with Groblersdal via Kempton Park, Bapsfontein and Bronkhorstspruit.

It makes its way north-east through the suburb of Sandringham, crossing the Jukskei River, bypassing Edenvale Hospital, before crossing the N3 highway (Johannesburg Eastern Bypass) as a dual carriageway and passing by Greenstone Hill, where Greenstone Shopping Mall is located.

Right after, it crosses the R21 highway between Pretoria and Johannesburg International Airport and makes a direct line for Bapsfontein.

It intersects with the N4 Highway (Maputo Corridor) and the R104 road (both coming from Pretoria in the west) and goes northwards through Bronkhorstspruit.

[1] Afterwards, the R25 temporarily goes into Mpumalanga, where it bypasses Wolvenkop and intersects with the R544 from Witbank in the town of Verena, before proceeding into Limpopo province, where it passes through Dennilton before ending in the vicinity of the small farming town of Groblersdal, terminating at a junction with the N11 and the R33.