The R334 is a Regional Route in the Nelson Mandela Bay Metropolitan Municipality of South Africa that connects the N2 west of Gqeberha to the N2 at Coega north of Gqeberha via Uitenhage.

[2] The R334 begins at a junction with the N2 national route north-east of Gqeberha (7.5 km south-west of Colchester), heading west-south-west.

It is initially co-signed with the R102 for 10 kilometres before the R334 becomes its own road westwards named Daniel Pienaar Street.

[1] It leaves the town to the south-west, crossing the Swartkops River to become Cape Road and passing the township of KwaNobuhle.

It ends at a junction with the R102 to the west of Gqeberha (east of Van Stadens Wild Flower Reserve), near an interchange with the N2.