The R552 is a Regional Route in the City of Johannesburg Metropolitan Municipality in Gauteng, South Africa.

[1] Its north-western terminus is a junction with the M5 (Beyers Naudé Drive) at a place named Elandsdrift.

It heads eastwards as Elandsdrift Road to reach a junction with the R512 (Malibongwe Drive; Pelindaba Road) at Bultfontein, just south of the Lanseria International Airport entrance.

It continues south-east as 6th Avenue to fly over the N14 highway and reach a staggered junction with the R114 (Lion Park Road).

[1] From the R114 junction, it continues south-east as Cedar Road, through the suburb of Dainfern, through the suburbs of Broadacres and Craigavon, to reach its end at a junction with the R564 (Witkoppen Road) in Fourways, Sandton.