The R720 is a Regional Route in Free State, South Africa that connects Vredefort with Senekal via Koppies, Edenville and Steynsrus.

[1] Its northern terminus is a junction with the R721 about 4 km south of Vredefort.

From there, it heads south-east, crossing the N1, to reach Koppies, where it meets the R82.

From there, it heads south for 29 km to reach a junction with the R34.

From Edenville, it heads south for 46 km to Steynsrus, where it crosses the R76.