The R73 is a provincial route in Free State, South Africa that connects Welkom with Winburg via Virginia.

[1] The R73 begins in Welkom (west of the town centre), at a junction with the R30 road.

The R73 joins the M1 northwards up to the next roundabout, where the R73 becomes its own road eastwards as Jan Hofmeyr Street.

The R730 joins the R73 and they are co-signed southwards on the dual carriageway for 10 kilometres before the R73 leaves the ZR Mahabane Highway (R730) and becomes its own road eastwards.

[1] The R73 goes eastwards through the northern suburbs of Virginia (Saaiplaas and Harmony) for 9 kilometres up to a 4-way-junction, where the R73 becomes the road southwards, proceeding to cross the Sand River in the eastern suburbs of Virginia.