The main occupier of the station was 44 Squadron, with the Avro Lancaster four-engined heavy bomber, which moved in from RAF Waddington in May 1943 and stayed until it moved to RAF Spilsby in September 1944.

At the end of the war 120 Lancasters had been lost on operations from Dunholme Lodge.

From 1948 the site was host to motorcycle and car racing until 1959 when the base was reopened as an active RAF station.

[2][3] The William Farr School was opened in 1952 on part of the disused domestic site.

On re-opening in 1959, the airfield became a site for Bristol Bloodhound surface-to-air missiles with 141 Squadron until it was disbanded and the station finally closed in 1964.