[5][6] This gene encodes a protein with a conserved RNA-binding motif.

The protein is found predominantly in the nucleus, although it is also present in the cytoplasm.

It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events.

Two alternative start codons result in two forms of the protein, and this gene also uses multiple polyadenylation sites.

[11] This article on a gene on human chromosome 1 is a stub.