2V1X, 2WWY, 4U7D596519691ENSG00000004700ENSMUSG00000030243P46063Q9Z129NM_002907NM_032941NM_001204906NM_001204907NM_023042NM_001355511NP_002898NP_116559NP_001191835NP_001191836NP_075529NP_001342440ATP-dependent DNA helicase Q1 is an enzyme that in humans is encoded by the RECQL gene.

[5][6][7] The protein encoded by this gene is a member of the RecQ DNA helicase family.

Some members of this family are associated with genetic disorders with predisposition to malignancy and chromosomal instability.

Two alternatively spliced transcripts, which encode the same isoform but differ in their 5' and 3' UTRs, have been described.

[7] RECQL has been shown to interact with KPNA4[8] and Karyopherin alpha 2.