Sometime in 1948, Henry Canoy, together with Robin Cui and Vicente Rivera, set up two home-built tube radio receivers bought from Fideng Palacio of Puntod and placed them in an abandoned chicken poultry house situated at the corner of Velez and del Pilar streets in Cagayan de Oro for the purpose of listening to radio broadcasts from Manila.

The group managed to assemble a 30-Watt radio transmitter from surplus parts bought at Raon Street in Quiapo, Manila.

Canoy broke the airwaves as a pirate radio station in 1949, declaring "This is Cagayan de Oro calling...".

In 1951, he set up the fledgling station in partnership with Robin Cui, Max Suniel, Oscar Neri and Andres Bacal as equity partners with P10,000 in capital.

Using the Radio Amateur's Handbook as their guide and also with surplus parts bought from Raon Street in Quiapo, they built their own 500-watt AM transmitter with the assistance from Far East Broadcasting Company engineers, American Dick Rowland and Byrd Bruneimer.

With only a telescopic steel pole as antenna borrowed from the Bureau of Telecom, the improvised horizontal radio antenna was mounted by the team which include Ongkoy Padero, former vice president for engineering of CEPALCO, attaching one end of a copper wire to the pole and the other end to a 30 meter coconut tree a block away .

It officially started broadcasting on August 28, 1952, also coinciding with the town festival of San Agustin, the patron saint of Cagayan de Oro.

The station's first live broadcast coincided with its opening and the program involved the airing of a three-hour “Anejo Rum” show from Plaza Divisoria, a central park in downtown Cagayan de Oro, for which Canoy billed La Tondena executive Hugo Chan Hong the sum of P500 as payment for the radio coverage.

Instead of going to the giant networks and other big cities, he opted to be taken to a small town of Greeley, Colorado, and he came upon a station that was doing exactly what DXCC was already trying to do in Mindanao.

Its broadcast fare was peppered with farm prices, market and road conditions, weather warnings and personal messages.

RMN joined forces with the Philippine Herald and Inter-Island Broadcasting Corporation to form the powerful first tri-media organization.

Other "Sound of the City" stations soon followed in Zamboanga City in 1961 (DXRZ), Cebu in 1962 (DYHP), Metro Manila (DWXL) (now DZXL) and Iloilo in 1963 (DYRI), Bacolod in 1964 (DYHB), Tagbilaran in 1967 (DYXT), Baguio (DZHB) and Bislig, Surigao del Sur in 1968 (DXHP).

Among the stations that were added to the roster of RMN stations were: DXMD in General Santos, DWHP-FM in Laoag, DYRR in Ormoc, DXWR-FM in Zamboanga City, DXIX-FM in Iligan, DYXY-FM in Tacloban, DYRS in San Carlos, Negros Occidental, DXVM-FM in Cagayan de Oro, DXMB-AM in Malaybalay, DXXL-FM in Davao City, DYXL-FM in Cebu, DWKC-FM in Metro Manila and DXKR-AM in Koronadal, DYKR-AM in Kalibo in 1979.

DXDR-AM in Dipolog and DXPR in Pagadian was added on January 10, 1980, DXXX-FM in Butuan in 1985, DYVR-FM in Roxas, Capiz in 1986 and DYIC-FM in Iloilo City in 1987.

Under this scheme, RMN provided programming, marketing, technical and management expertise where these small stations would be found wanting.

During the early 90s, DYHP in Cebu was also aired their programs via satellite thru the stations DYHD in Tagbilaran, DYRR in Ormoc, DYWC in Dumaguete, DYRS in San Carlos, DXDR in Dipolog and DXRS in Surigao.

In December 1991, RMN was also granted a permit to operate a UHF television station in Metro Manila (which was led to officially started two years later, on October 31, 1993; the frequency was now used by Broadcast Enterprises and Affiliated Media, Inc. (throughGlobe Telecom's then-subsidiary Altimax Broadcasting Company)).

In 1998, it went global by establishing the first Philippine radio station to conquer the United States airwaves through WRMN in New York City.

DWKC-TV and other regional stations were soon acquired by Broadcast Enterprises and Affiliated Media (then under the Canoys until it was sold to the Globe Group in 2009) and resumed its operations in 2011.

10818, renewing the franchise granted to the Radio Mindanao Network, Inc. for another twenty-five (25) years on a term that shall take effect on April 18, 2016.

[11] RMN broadcasts a number of national programs either through a localized version or via satellite from the network's main studios in San Juan.