Widely produced, the most commonly seen major variations are the RPG-7D (десантник – desantnik – paratrooper) model, which can be broken into two parts for easier carrying; and the lighter Chinese Type 69 RPG.

DIO of Iran manufactures RPG-7s with olive green handguards, H&K style pistol grips, and a commando variant.

The current model produced by the Russian Federation is the RPG-7V2, capable of firing standard and dual high-explosive anti-tank (HEAT) rounds, high explosive/fragmentation, and thermobaric warheads, with a UP-7V sighting device fitted (used in tandem with the standard 2.7× PGO-7 optical sight) to allow the use of extended range ammunition.

The TRADOC bulletin provides anecdotal commentary that the RPG-7 has been fired from within buildings, which agrees with the two-stage design.

It is stated that only a 2 metres (6.6 feet) standoff to a rear obstruction is needed for use inside rooms or fortifications.

A crosswind will tend to exert pressure on the stabilizing fins, causing the projectile to turn into the wind (see Weathervane effect).

The TRADOC bulletin explains aiming difficulties for more distant moving targets in crosswinds at some length.

[citation needed] The Russian Ministry of Defense said in December 2023 that it has modified the RPG-7V grenade launcher in order to shoot 82-mm mines.

[10] Current production ammunition for the RPG-7V2 consists of four main types: Other warhead variants include: Manufacturer specifications for the RPG-7V1.

[31] On 28 August 2003, it achieved a mobility kill against an American M1 Abrams hitting the left side hull next to the forward section of the engine compartment.