2CQA, 2XSZ, 3UK61085620174ENSG00000183207ENSMUSG00000003868Q9Y230Q9WTM5NM_006666NM_001321190NM_001321191NM_011304NP_001308119NP_001308120NP_006657NP_035434RuvB-like 2 (E. coli), also known as RUVBL2, is a human gene coding for a protein belonging to the AAA+ family of proteins.
Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair.
However, the evidence for whether RUVBL2 has DNA helicase activity is contradictory.
[6] RUVBL2 has been shown to interact with RuvB-like 1[7] and Activating transcription factor 2.
This article on a gene on human chromosome 19 is a stub.