He remains a virgin until his brash cousin Danny (Alex Rocco) sets him up with a one-night stand.

Soon after, Lionel starts feeling nauseated and vomits, eventually doing so onto Segoynia Savaka (Joan Prather), one of his immigrant students.

When Lionel meets Segoynia's fortune-telling grandmother (played by Roddy McDowall in drag), she intuits that he is the world's first pregnant man.

One side plot has Lionel being pursued by the Army because the President of the United States is afraid of what effect the widespread ability of men to conceive will have on population growth.

Despite the negative reviews the film received, Rabbit Test was a box office hit, grossing over $12 million in its first four months of release.