The women's singles competition of the racquetball events at the 2011 Pan American Games will be held from October 17–22 at the Racquetball Complex in Guadalajara, Mexico.

[1] The defending Pan American Games champion is Cheryl Gudinas of the United States, while the defending Pan American regional champion from 2011 is Rhonda Rajsich also of the United States.

[2] All times are Central Standard Time (UTC-6).

The round robin will be used as a qualification round.

Groups will be announced at the technical meeting the day before the competition begins.