[5] Guzmán knocked out Ernesto González to win the WBC FECARBOX lightweight title and then he won the WBC Mundo Hispano lightweight title by stopping the veteran Jorge Martínez.
[6] On January 24, 2009 Guzmán upset contender Isaac Bejarano to win the WBC FECARBOX super featherweight title.
He won his third title in front of his hometown at the Coliseo Olimpico de la UG in Guadalajara, Jalisco, Mexico.
[7] In June 2011, Guzmán lost to an undefeated Mikey Garcia on HBO's undercard of Sebastian Zbik vs. Julio César Chávez Jr..[8] On October 18, 2011 Guzmán was shot eight times before dying in his hometown of Guadalajara, Jalisco.
[9] In a case of mistaken identity, Rafael had survived a previous attack when on his way to see the birth of his fourth child his vehicle was shot eleven times.