Ortega began his professional career on January 24, 1970, in Colon City, Panama against Roberto Javier.
Ortega would fight for the first time outside of Panama on February 16, 1972, as he travelled to New York City, United States to face Fernando Jimenez.
Ortega arrived in New York with an unbeaten record after 9 fights (including 4 draws) and further added to his wins with an eight-round decision victory.
Ortega retained his title with another unanimous decision and in the process knocked Uehara down in the first and fourth rounds with left uppercuts.
An estimated crowd of 6,300 saw Lastra knockdown Ortega in the third round with a solid left jab and win the title via split decision after dominating the fight.