Both father and son are profiled in Vasari's Le Vite delle più eccellenti pittori, scultori, ed architettori (or, in English, Lives of the Most Excellent Painters, Sculptors, and Architects).
As a young artist in his twenties, he assisted Lorenzetto in Rome with the execution of statues of Elijah and Jonah for the Chigi Chapel in Santa Maria del Popolo (on designs by Raphael).
Raffaello then went to Loreto, where the Visitazione and Adorazione dei Magi (c. 1534) at the Basilica of the Holy House (Chiesa della Casa Santa) are attributed to him (on designs by Andrea Sansovino).
[1] Shortly thereafter, according to Vasari, Raffaello began work in Florence with Michelangelo, at the Medici Chapel of the Basilica di San Lorenzo, for which he sculpted Saint Damian (c.
Raffaello da Montelupo also worked as an architect and, among other projects, made both sculptural and architectural contributions to the Duomo in the Umbrian town of Orvieto, where he retired and later died in 1566/1567.
[1]In the 1560s, Raffaello wrote something of a partial autobiography, recounting episodes from his youth, the sack of Rome in 1527 by the army of Charles V, Holy Roman Emperor, and Montelupo's work as a budding artist and sculptor during this period.