Raine syndrome (RNS), also called osteosclerotic bone dysplasia, is a rare autosomal recessive congenital disorder characterized by craniofacial anomalies including microcephaly, noticeably low set ears, osteosclerosis, a cleft palate, gum hyperplasia, a hypoplastic nose, and eye proptosis.

However, a recent report describes two studies in which children with Raine syndrome have lived to 8 and 11 years old, so it is currently proposed that there is a milder expression that the phenotype can take (Simpson 2009).

Dental pain Cavities and dental issues Bone aches and pains Causes other chronic health issues Tiredness Aches Raine syndrome appears to be an autosomal recessive disease.

Simpson et al.'s (2007) report states that to date, effected individuals have had chromosome 7 uniparental isodisomy and a 7p telomeric microdeletion.

The patient born in BC had multiple dental surgeries to help fix the symptoms of raine syndrome but her chronic illnesses affect daily.