Laryngo-onycho-cutaneous syndrome (also known as Shabbir syndrome) is a rare epithelial disorder inherited in an autosomal recessive fashion.

[1][2] It is characterized by abnormalities in the larynx, nails ("onycho-"), and skin ("cutaneous").

[3] The disorder is only found in Punjabi Muslims and only a few cases have been reported.

[4] It was characterized by Pakistani dermatologist Syed Ghulam Shabbir (1923–2002)[5] in 1986.

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