The film begins with three youngsters - Ashwin, Kishore, and Praveen - who are friends from college days, deciding to lead a life by investing in a resort business.

The Father suggests they approach a world-renowned mentalist named Rudra who has parlor tricks, mental tenacity to make clever guesses, special powers of contacting with the spirits, and also assists the Police Department as a human lie detector with his cold reading techniques.

After knowing the truth, Amrutha tries to kill Kiran, but Rudra stops her way by reminding the morals taught by her father and making her soul rest in peace.

All lyrics are written by Ramajogayya Sastry; all music is composed by S. ThamanRaju Gari Gadhi 2, a new project with Nagarjuna Akkineni in the lead was launched on 27 November 2016 at Annapurna Studios, K. Raghavendra Rao gave the clap for the first scene, producer Prasad V Potluri switched on the camera while Omkar directed the first shot.

Times of India gave 3 out of 5 stars stating "The linear narrative and lack of spooks in what’s touted to be horror-comdey [sic] not withstanding, Raju Gari Gadhi 2 makes for a passable weekend watch".