Ramkarran qualified as a lawyer in 1972 in the United Kingdom as a member of Gray's Inn and returned to Guyana the following year when he entered into private practice.

Ramkarran has spoken and lectured widely on behalf of the People's Progressive Party (PPP) in Guyana and was the editor of its official journal, the Thunder, between 1992 and 2002.

[citation needed] In 1994 he was elected as the Guyana Facilitator to the United Nations Good Officer Process under the Geneva Agreement relating to the Guyana-Venezuela Border controversy.

[citation needed] His father, Boysie Ramkarran, served as British Guiana's, Minister of Works and Communications in the 1957/61 PPP government and immediately after that Boysie Ramkarran served as Minister of Works and Hydraulics in the 1961/1964 PPP government and he was also the General Secretary of GAWU between 1975 and 1985.

[citation needed] On 29 June 2012, at an executive party meeting Ramkarran proclaimed he received many hostilities as a result of an article he wrote about corruption.