Rama II Road (Thai: ถนนพระรามที่ 2, RTGS: Thanon Phra Ram Thi Song; usually shortened to ถนนพระราม 2, Thanon Phra Ram Song) or Highway 35 (ทางหลวงแผ่นดินหมายเลข 35, Thang Lauang Phaendin Mai Lek 35) is a road in Thailand heading towards the south.

Rama II Road was built during the government of Field Marshal Thanom Kittikachorn with a total budget of approximately 419 million baht and was officially opened on 1 April 1973.

A side effect of the road's construction was that the Maeklong Railway line became less frequented and unprofitable, but still could not be retired due to some villages remaining accessible only by train.

Including criticism that popular tourist destination like Hua Hin are lonely and empty of people.

[3][4] At 4:13am on November 29, 2024, launching gantry crane and precast concrete segments on the outbound side of Rama II Road at the construction site of the Ekkachai - Ban Phaeo Intercity Motorway 82 (M82) section in Khok Krabue Subdistrict, Mueang Samut Sakhon District, Samut Sakhon Province collapsed, resulting in six deaths and eight injuries.