Ramkamal Sen (1783–1844) was the Diwan of the Treasury, Treasurer of the Bank of Bengal and Secretary of the Asiatic Society, Calcutta.

His grandson was the pre-eminent social reformer and founder of the Nababidhan Brahmo Samaj, Keshab Chandra Sen"[2] A self-made man, starting as a petty compositor earning eight rupees a month,[3] "He worked for several years in a Hindustani press after which he was appointed as a clerk in the Asiatic Society".

After a failed first attempt to remove Derozio from the school for preaching Christianity, he also became principal of the newly established Sanskrit College for sometime.

Sastri wrote: "Babu Ramkamal Sen acting as their mouthpeice, ... called a Committee meeting, and moved that Mr Derozios's manners and conduct was such as to injure the morals of the boys in touch with him and he should be removed from the staff of masters.

He publicly opposed (with Radhakanta Deb) Roy's agitation against sati (the practice of forcing Hindu widows to be burnt on their husbands funeral pyre).