A member of the Nationalist People's Coalition, he was elected to the House of Representatives of the Philippines in a 2005 special election, succeeding his brother Joseph Ace Durano as the Representative of the Fifth District of Cebu, following his appointment as Secretary of the Department of Tourism.

He has authored various legislation aimed at socio-economic development particularly the reclassification of the Camotes Islands from timberland into alienable and disposable in order to usher in unprecedented economic growth.

He allocated appropriations at the Vicente Sotto Memorial Medical Center, Danao Provincial Hospital, Everseley Childs Sanitarium.

Red Durano as he is fondly called by the people finished his bachelor's degree from the College of Notre Dame in Belmont, California.

He is the son of Danao Mayor Ramon "Nito" D. Durano III who also served for nine years as the Congressman of the same district.