Low,[2] Vicente de la Serna was born in Butuan, Agusan del Norte on September 13, 1951.

[1] He was known as an anti-Marcos activist in Cebu in the 1980s and later appointed in charge of the Office of the Mayor of Mandaue City when Corazon Aquino became president after the 1986 EDSA revolution.

In 1987, he ran for a legislative seat and won as member of the 8th Congress of the Republic representing Cebu's 6th district.

Negotiations for a land swap deal between the provincial and city governments that would allow the residents to own the lot by paying a monthly amortization commenced and lasted for over two decades.

[1] During the administration of Joseph Estrada, Vicente de la Serna was appointed deputy executive secretary.