He was abducted and later found dead in 2002, following a series of events marking the eighth anniversary of the imprisonment of Lebanese Forces party leader Samir Geagea.
After being released, Irani organized peaceful protests against the Syrian-occupied government of Lebanon and faced continuous harassment from Lebanese authorities.
On 9 May 2002, Amnesty International issued a statement to express the fear that Irani could be detained incommunicado and subjected to torture.
[citation needed] A newsportal, Al Qanat, revealed they had received a report saying that Irani had been murdered because they feared he would speak out about his abductors and that it would have created a "big political crisis."
Ramzi Irani's murder is still a cold case like many other brutal assassinations which have occurred against opponents of the Syrian occupation of Lebanon during the recent years.