He is known to have involved in advanced research in plant genetic studies and has written over 240 articles,[2] and 22 books[3] including Essentials of Biotechnology[4] and Emerging Trends in Biomedical Science and Health.

[8] The Government of India awarded him the fourth highest civilian honour of the Padma Shri, in 2009, for his contributions to Literature and Education.

He served the institution in various capacities such as Curator (1975–1976), Lecturer (1976–1985), Reader (1985–1994) and Professor in Cell Biology (1994–2006) when he was appointed as the vice chancellor of the university.

[15] Sobti is married to Vipin Khindagi; the marriage took place on 8 October 1975, while he was working as a curator at Panjab University.

[6] With the funding, he helped establish regional centres and colleges in rural areas and initiated programs to provide preferential admission to AIDS/Thalassemia patients and single girl child families at the affiliated colleges and university campus and provided free education to orphans and differently abled students.

[6] The university also took up the responsibility to adopt 8 nearby villages and set up facilities there for computer literacy, community health and language learning.

[16] It was under his vice chancellorship at the Babasaheb Bhimrao Ambedkar University, the institution started its collaboration with Uttar Pradesh Council for Science and Technology (UPCST) and North Eastern Railway (NER), Lucknow Division for innovations in the public sector services.

[6] He has handled several projects for University Grants Commission, Council of Scientific and Industrial Research, Indian Council of Medical Research, Department of Biotechnology and the Ministry of Human Resource Development and has been a member of the Editorial Boards of journals such as Molecular and Cellular Biochemistry,[21] Cytology and Genetics, and the Indian Journal of Human Genetics.