Rancho Esquon (also called Neal's Rancho) was a 22,194-acre (89.82 km2) Mexican land grant in present-day Butte County, California given in 1844 by Governor Manuel Micheltorena to Samuel Neal.
Samuel Neal (1816–1859), a native of Pennsylvania and a blacksmith by trade, came to California with John C. Frémont's second expedition in 1844.
After working for John Sutter briefly, Samuel Neal was awarded the five square league Rancho Esquon grant in 1844.
With the cession of California to the United States following the Mexican-American War, the 1848 Treaty of Guadalupe Hidalgo provided that the land grants would be honored.
Durham sold 17,800 acres (72.0 km2) in the southerly part of Rancho Esquon to George Gridley and his eldest son, C.E.