As a music producer, he has worked with artists and filmmakers including Danny Elfman, Jim Jarmusch, Panos Cosmatos, Nathan Fielder, Benny Safdie, Guillermo Del Toro, Björk, Oneohtrix Point Never, Thurston Moore, Zola Jesus, Algiers, Sunn O))), SQÜRL, Six Organs of Admittance, Marissa Nadler, Boris, Anna Von Hausswolff, Pallbearer, Oren Ambarchi, Eyvind Kang, The Cave Singers, Akron/Family, Earth, Wolves in the Throne Room, and Jesse Sykes, among others.

[3] He attended the Art Institute of Seattle to study sound design for film,[4] and formed connections with local musicians, including Skerik and Matt Chamberlain.

[3] In 1998 he engineered the live portion of the album Bumpa by Critters Buggin,[9] while he received a writing credit for his involvement with Mr. Birdy's Fryday by the Rockin' Teenage Combo.

[14] In the same year, Dunn met Dylan Carlson of the band Earth in Seattle and recorded their fourth album, Hex; or Printing in the Infernal Method at Aleph Studios.

[15] After hearing his work with Asva, Stephen O'Malley contacted Dunn to produce the collaborative album between Sunn O))) and Boris, Altar.

The Association of Danish Music Critics nominated Randall Dunn for Producer of the Year in 2018 for his work with Sort Sol, Myrkur, and Childrenn.

AllMusic described the record as “[...] extend[ing] the reach of their previous outings while offering a more strategically articulated, disciplined musicality without sacrificing their core sound or blunting their emotional impact.”[28] Dunn produced Zola Jesus’ sixth studio album Arkhon, issued by Sacred Bones in 2022.

[31] In addition to his work as a producer and engineer, Dunn is a keyboardist and founding member of the experimental group, Master Musicians of Bukkake.

[7] In 2004, alongside his bandmates, Dunn wrote, arranged and produced the first Master Musicians of Bukkake record, The Visible Sign of the Invisible Order.

The album was released on Sun City Girls' label, Abduction Records and featured the musicians Eryn Young (vocals), James Davis, Don McGreevy, Alan Bishop, Charlie Gocher, and John Schuller.

[34] In 2014, Dunn worked with Oren Ambarchi and Stephen O’Malley on scoring the short film Kairos by the Belgian filmmaker Alexis Destoop.

[2] Dunn co-produced and composed additional music for the score to the Panos Cosmatos film Mandy, along with the late Jóhann Jóhannsson in 2018.

[36] In 2021, Dunn produced Robert Aiki Aubrey Lowe’s score to the Nia DaCosta film Candyman, with a screenplay by Jordan Peele.

[38] In the same year, Dunn and Hansson composed the score for The Way of the Psychonaut, a documentary about the life and work of Stanislav Grof, founder of transpersonal psychology.

[39] Dunn was the musical director and producer of Daniel Lopatin’s score to The Viewing, the 2022 Panos Cosmatos episode of Guillermo Del Toro's Cabinet of Curiosities.

[7] On several occasions, Dunn has expressed a preference for the use of analog recording equipment: "I'm not a huge fan of the predictability of digitally processed music.