Most guests are considered long term, meaning they stay for more than thirty consecutive days.

The Randolph Hotel is located on the corner of Fourth Street and Court Avenue downtown, along the historic Court Avenue strip.

It is located at 200-204 4th Street in the downtown commercial district of Des Moines.

[2] The property was added to the National Register of Historic Places (NRHP) on June 11, 2009, and the listing was announced as the featured listing in the National Park Service's weekly list of June 19, 2009.

[3] In 2008, rehabilitation of the building into low- and moderate-income rental housing, to be funded in part by federal and state historic preservation tax credits, was planned.