Salerno served as a general assignment reporter and as the weekend morning news anchor from 1994 till 1999.
Before working at WGN, Salerno was a reporter and weekend anchor at WNYT in Albany, New York.
He began his broadcasting career at WIFR-TV in Rockford, Illinois as a general assignment reporter.
Salerno passed away in a snowmobile accident on the night of January 24, 2008, on Plum Lake near Sayner/Eagle River, Wisconsin.
Randy Salerno won a local Emmy Award for his work on CBS 2's 2004 broadcast of the LaSalle Bank Chicago Marathon.