As a child, she read freely in her family library and she later attended Damascus University to study Arabic literature.
She founded the Al-Sindiyan Festival of Literature and Culture in her hometown in the late 1990s, which she directed for 16 years, and published her first poems after the death of her father.
“This is a dictatorial regime, [....] How can I support a government that kills its citizens?”[3] She has marched in protests, written about her dissent, and spoken out against Assad.
In September 2012, Omran and four other Syrian women launched a hunger strike outside the Arab League's headquarters in Tahrir Square, Cairo, Egypt, demanding that the Arab League provides more support for the revolutionaries, and pressure Assad to halt the human rights abuses in Syria.
[7][8] She has lived in Cairo since 2012 where she continues to write and publish her poetry, as well as three weekly articles for online Arab media where she comments on political and cultural news.