[13] In 2007, Buttar was brought before the North Carolina Board of Medical Examiners, accused of unprofessional conduct for providing ineffectual therapies to four cancer patients.
[5][19] He came to public attention in 2009 when he alleged to have successfully used chelation therapy to treat Desiree Jennings, a Washington Redskins cheerleading ambassador who had made dubious claims about having dystonia and losing her ability to walk or talk normally after receiving a flu shot.
In July 2009, Buttar and his wife Debbie achieved the rank of "blue diamond" within the distributor network of the multi-level marketing company Monavie, which sold an acai-based beverage until going into foreclosure in 2015.
[24] In April 2010, the FDA sent Buttar a warning letter for illegally marketing unapproved topical creams as drugs via his websites, YouTube videos, and radio appearances.
[5][6] FDA inspections also revealed that Buttar's company, V-SAB Medical Labs, had not complied with good manufacturing practices and that its products were adulterated according to the Federal Food, Drug, and Cosmetic Act.
"[31] Buttar promoted anti-vaccination videos sold by Ty and Charlene Bollinger and received a commission whenever his referrals resulted in a sale, a practice known as affiliate marketing.