At the 2005 World Amateur Boxing Championships in Mianyang he avenged a previous loss to European champion Georgy Balakshin before losing to the Korean surprise winner Lee Ok-Sung and having to settle for bronze.

He remained in the amateur ranks and ascended to the bantamweight division again at the US Nationals 2009 where he controversially lost his semifinal 19:19 (countback loss) to eventual champion Jesus Magdaleno.

On August 3, 2012 at the London Olympics, Rau'shee Warren failed to get past the first round of the brackets yet again for the third time of his amateur career losing to Nordine Oubaali of France in a close decision of 19-18.

Having won thirteen of his first fourteen fights (the only blemish being a three-round no contest against Javier Gallo on December 12, 2014), Warren attempted to win his first world championship—the WBA (Undisputed) and vacant IBO bantamweight titles—on August 2, 2015, but lost a debatable split decision to Juan Carlos Payano.

[4] In his next fight against Juan Gabriel Medina, Warren had another dominant performance and defeated his opponent via unanimous decision, winning every single round on all of the scorecards.

[5] On September 5, 2018, it was announced that Warren would face former Olympics opponent Nordine Oubaali for the WBC bantamweight title, previously vacated by Luis Nery.